Best Cities in South America to Live, Work & Travel Sort by Alphabetical Global Score Population Safety Cost of Living Climate Environment Culture Transportation Healthcare Education Commerce & Services Economic Opportunities Buenos Aires Argentina 7.8/10 15,300,000 inhabitants Profile: Foodies Nightlife Leisure View City Medellin Colombia 7.8/10 2,569,000 inhabitants Profile: Digital Nomads Budget Students View City Lima Peru 7.2/10 9,700,000 inhabitants Profile: Foodies Leisure Nightlife View City Bogota Colombia 7.2/10 8,000,000 inhabitants Profile: Budget Nightlife Digital Nomads View City Page 1 / 1